COX7A2 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]

Mitochondrion. Cytochrome c oxidase subunit 7A2, mitochondrial; COX7a related protein; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-liver/heart; COX7a-related protein; COX7AR; COX7RP; Cytochrome c oxidase subunit VIIa related protein, mitochondrial; Cytochrome c oxidase subunit VIIaL; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-related protein, mitochondrial [Precursor]; EB1; Estrogen receptor binding CpG island; SIG81; CX7A2_HUMAN.