ICOS ligand Polyclonal Antibody
Product Specifications
Background
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity) .
Synonyms
B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L; ICOS ligand; B7 homolog 2; B7-like protein Gl50; B7-related protein 1; ICOSLG; KIAA0653
Gene ID
23308
Swiss Prot
O75144
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
19-120/302
Target
ICOS ligand
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from Rat ICOS-L
Applications
WB, ELISA, FCM
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
23308
Predicted Cross Reactivity
Rat
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