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ICOS ligand Polyclonal Antibody

Product Specifications

Background

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity) .

Synonyms

B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L; ICOS ligand; B7 homolog 2; B7-like protein Gl50; B7-related protein 1; ICOSLG; KIAA0653

Gene ID

23308

Swiss Prot

O75144

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

19-120/302

Target

ICOS ligand

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from Rat ICOS-L

Applications

WB, ELISA, FCM

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

23308

Predicted Cross Reactivity

Rat

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