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TNFSF18 Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.

Synonyms

TL6; AITRL; GITRL; hGITRL; Tumor necrosis factor ligand superfamily member 18; Activation-inducible TNF-related ligand; Glucocorticoid-induced TNF-related ligand; TNFSF18; UNQ149/PRO175

Gene ID

8995

Swiss Prot

Q9UNG2

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

101-199/199

Target

TNFSF18

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human TNFSF18

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8995

Predicted Cross Reactivity

Rat

Curated Selection

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