Integrin alpha 5 Polyclonal Antibody

CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5) ; in platelets as glycoprotein IcIIa; and in fibroblasts as extracellular matrix receptor 6 (ECMVI) . In addition to adhesion, integrins are known to participate in cell surface mediated signalling.

Integrin alpha-5 light chain; Alpha 5 beta 1; CD49 antigen-like family member E; CD49e; ECMRVI; Fibronectin Receptor alpha; Fibronectin receptor alpha subunit; Fibronectin receptor, alpha subunit; FNR; FNRA; gpIc/IIa; Integrin alpha 5 (fibronectin receptor alpha) ; Integrin alpha 5; Integrin alpha F; Integrin alpha-5; Integrin alpha-F; Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) ; ITGA5; Very late Activation Antigen 5; Very Late Activation Protein 5 alpha; Very late activation protein 5, alpha subunit; VLA5; VLA5A; ITA5_HUMAN; Integrin α5; Integrin-α5.