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Apelin Receptor Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Synonyms

APJ; APJR; HG11; AGTRL1; Apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11; APLNR

Gene ID

187

Swiss Prot

P35414

Cellular Locus

Cell membrane, Cytoplasmic domain

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

52-66/380

Target

Apelin Receptor

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human Apelin receptor (cytoplasmic domain)

Applications

WB, FCM

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

187

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