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Apelin Receptor Polyclonal Antibody

Product Specifications

Background

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Synonyms

APJ; APJR; HG11; AGTRL1; Apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11; APLNR

Gene ID

187

Swiss Prot

P35414

Cellular Locus

Cell membrane, Cytoplasmic domain

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

52-66/380

Target

Apelin Receptor

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Apelin receptor (cytoplasmic domain)

Applications

WB, FCM, IHC-P, IF (IHC-P)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

187

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