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NCR3 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Synonyms

1C7; MALS; CD337; LY117; NKp30; Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NCR3

Gene ID

259197

Swiss Prot

O14931

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

81-180/201

Target

NCR3

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human NCR3

Applications

FCM

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

259197

Predicted Cross Reactivity

Rat, Dog, Horse, Rabbit

Curated Selection

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