NCR3 Polyclonal Antibody
Product Specifications
Background
Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
Synonyms
1C7; MALS; CD337; LY117; NKp30; Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NCR3
Gene ID
259197
Swiss Prot
O14931
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
81-180/201
Target
NCR3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human NCR3
Applications
ELISA, FCM, IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
259197
Predicted Cross Reactivity
Rat, Dog, Horse, Rabbit
Curated Selection
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