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Amphiphysin Polyclonal Antibody

Product Specifications

Background

Amphiphysin is associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff man syndrome who were also affected by breast cancer are positive for auto against this protein. Alternate splicing of this gene results in two transcript variants (Amphiphysin 1 and Amphiphysin 2) encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined.

Synonyms

Amphiphysin; Amp; AMPH 1; AMPH1; Amphiphysin Stf-Man syndrome with breast cancer 128kD autoantigen; Amphiphysin Stf-Man syndrome with breast cancer 128kDa autoantigen; Amphiphysin I; CG8604; Damp; dAmph; Dmel\CG8604; HGNC:471; MGC49429; Stf man syndrome with breast cancer 128kD autoantigen; Stf man syndrome with breast cancer 128kDa autoantigen; AMPH_HUMAN.

Gene ID

273

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

101-200/695

Target

Amphiphysin

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Amphiphysin

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

273

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Horse, Chicken, Rabbit

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