MET kinase-IN-2
MET kinase-IN-2 is a potent, selective, orally bioavailable MET kinase inhibitor with an IC50 of 7.4 nM. MET kinase-IN-2 has antitumor activity[1].
Product Specifications
CAS Number
[2101241-90-9]
UNSPSC
12352005
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/met-kinase-in-2.html
Purity
98.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C2=CC=CC=C2)=CNC3=C1C(NC4=CC=C(OC5=CC=NC6=CC(OCC(C)(O)C)=CC=C56)C(F)=C4)=NC=C3
Molecular Formula
C33H27FN4O4
Molecular Weight
562.59
References & Citations
[1]Chen T, et al. Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate. Eur J Med Chem. 2020;192:112174.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0523307 1.0 µg DNA
CT47B1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
Sign In for Pricing
View Details 
![Mouse Monoclonal CUZD1 Antibody (M4P6G6) [CoraFluor 1]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP2-50186CL1 0.1 mL
Mouse Monoclonal CUZD1 Antibody (M4P6G6) [CoraFluor 1]
Sign In for Pricing
View Details 