TGF beta Receptor I Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Synonyms
TGFBR1; TGF Beta R1; TGF beta Receptor I; AAT 5; AAT5; Activin A receptor type II like kinase 53kDa; Activin receptor like kinase 5; ACVRLK 4; ACVRLK4; ALK 5; ALK5; Serine/threonine protein kinase receptor R4; SKR 4; SKR4; TbetaR I; TGF beta receptor type 1; TGF beta receptor type I; TGF beta type I receptor; TGFBR 1; TGFBR1 protein; TGFR 1; TGFR1; Transforming growth factor beta receptor I; TGF-βRI; TGFβRI; TGF-βR I; TGF-β RI.
Gene ID
7046
Swiss Prot
P36897
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
21-120/503
Target
TGF beta Receptor I
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TGF beta Receptor I
Applications
WB
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
7046
Predicted Cross Reactivity
Dog, Cow, Sheep, Pig, Horse, Rabbit
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