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TGF beta Receptor I Polyclonal Antibody, PE Conjugated

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

Synonyms

TGFBR1; TGF Beta R1; TGF beta Receptor I; AAT 5; AAT5; Activin A receptor type II like kinase 53kDa; Activin receptor like kinase 5; ACVRLK 4; ACVRLK4; ALK 5; ALK5; Serine/threonine protein kinase receptor R4; SKR 4; SKR4; TbetaR I; TGF beta receptor type 1; TGF beta receptor type I; TGF beta type I receptor; TGFBR 1; TGFBR1 protein; TGFR 1; TGFR1; Transforming growth factor beta receptor I; TGF-??R???????; TGF??R???????; TGF-??R ???????; TGF-?? R???????.

Gene ID

7046

Swiss Prot

P36897

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

111-210/503

Target

TGF beta Receptor I

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human TGF beta Receptor I

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7046

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

Curated Selection

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