TGF beta Receptor I Polyclonal Antibody
Product Specifications
Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
Synonyms
TGFBR1; TGF Beta R1; TGF beta Receptor I; AAT 5; AAT5; Activin A receptor type II like kinase 53kDa; Activin receptor like kinase 5; ACVRLK 4; ACVRLK4; ALK 5; ALK5; Serine/threonine protein kinase receptor R4; SKR 4; SKR4; TbetaR I; TGF beta receptor type 1; TGF beta receptor type I; TGF beta type I receptor; TGFBR 1; TGFBR1 protein; TGFR 1; TGFR1; Transforming growth factor beta receptor I; TGF-??R???????; TGF??R???????; TGF-??R ???????; TGF-?? R???????.
Gene ID
7046
Swiss Prot
P36897
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
111-210/503
Target
TGF beta Receptor I
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TGF beta Receptor I
Applications
WB, ELISA, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
7046
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
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