NQO1 Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Synonyms
Azoreductase; Cytochrome b 5 reductase; DHQU; DIA 4; DIA4; Diaphorase (NADH/NADPH) (cytochrome b 5 reductase) ; Diaphorase (NADH/NADPH) (cytochrome b-5 reductase) ; Diaphorase (NADH/NADPH) (cytochrome b-5 reductase) ; Diaphorase (NADH/NADPH) ; Diaphorase 4; Dioxin inducible 1; DT diaphorase; DT-diaphorase; DTD; Menadione reductase; NAD (P) H dehydrogenase [quinone] 1; NAD (P) H dehydrogenase quinone 1; NAD (P) H menadione oxidoreductase 1 dioxin inducible; NAD (P) H: menadione oxidoreductase 1 dioxin inducible 1; NAD (P) H:menadione oxidoreductase 1; NAD (P) H:Quinone acceptor oxidoreductase type 1; NAD (P) H:quinone oxidoreductase 1; NAD (P) H:quinone oxireductase; NMOR 1; NMOR I; NMOR1; NMORI; NQO 1; NQO1; NQO1_HUMAN; Phylloquinone reductase; Phylloquinone reductase; QR 1; QR1; Quinone reductase 1; Quinone reductase 1.
Gene ID
18104
Swiss Prot
Q64669
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
201-274/274
Target
NQO1
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from mouse NQO1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
18104
Curated Selection
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