KGYY15
KGYY15 (Mouse KGYY15) is a CD40 targeting peptide, which weakly inhibits the CD40-CD40L interaction with IC50 of more than 1mM. KGYY15 activates 33% NF-κB pathway at 100 μM[1].
Product Specifications
CAS Number
[1690215-31-6]
Product Name Alternative
Mouse KGYY15; KGYY15 peptide
UNSPSC
12352209
Target
TNF Receptor
Type
Peptides
Related Pathways
Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kgyy15.html
Purity
99.19
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
Molecular Formula
C84H129N21O22S
Molecular Weight
1817.12
References & Citations
[1]Bojadzic D, et al., CD40-targeting KGYY15 peptides do not efficiently block the CD40-CD40L interaction. Diabetologia. 2019 Nov;62 (11) :2158-2160.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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