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NFKB p65 (acetyl K310) Polyclonal Antibody, APC Conjugated

Product Specifications

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

Synonyms

NF-kB p65 (acetyl K310) ; NF-_B p65 (acetyl K310) ; RELA (acetyl K310) ; NF kB P65; NF-kB p65; NFKBp65; NF-_Bp65; p65 NF kappaB; p65 NFkB; NFKBp65; RELA; Transcription Factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65) ) ; V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian) ; v-rel reticuloendotheliosis viral oncogene homolog A; p65NFKB; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NFKB 3; NFKB3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells; TF65_HUMAN. NF_B-p65; NF_B p65; NF _B-p65; NF_Bp65

Gene ID

5970

Swiss Prot

Q04206

Modification Site

K310

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

NFKB p65 (acetyl K310)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated Synthesised acetylpeptide derived from human NFKBp65 around the phosphorylation site of Lys310

Applications

WB, FCM

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Acetylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5970

Predicted Cross Reactivity

Rat, Dog, Cow, Sheep, Pig, Horse, GuineaPig

Curated Selection

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