ATG13 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Synonyms
ATG13 autophagy related 13 homolog; ATG13_HUMAN; Autophagy related protein 13; Autophagy-related protein 13; FLJ20698; KIAA0652.
Gene ID
9776
Swiss Prot
O75143
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
41-140/517
Target
ATG13
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human ATG13
Applications
IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (IHC-P=1:400-800), IHC-F (IHC-F=1:400-800)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
9776
Predicted Cross Reactivity
Human, Dog, Sheep, Pig, Chicken, Rabbit
Curated Selection
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