Glucose 6 phosphatase 2 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
IGRP (islet specific glucose 6 phosphatase catalytic subunit related protein), also known as G6PC2, belongs to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyses the hydrolysis of glucose-6-phosphate. This hydrolysis is the terminal step in gluconeogenic and glycogenolytic pathways, and allows the release of glucose into the bloodstream. IGRP is found in pancreatic islets and does not exhibit phosphohydrolase activity. However, it is a major target of cell-mediated autoimmunity in diabetes.
Synonyms
G 6 Pase 2; G 6 Pase2; G6Pase 2; G6Pase2; G6PC 2; G6pc rs; G6pcrs; Glucose 6 phosphatase 2; Glucose 6 phosphatase, catalytic, 2; Glucose 6 phosphatase, catalytic, related; Glucose 6 phosphate catalytic 2; Islet specific G6CP related protein; Islet specific glucose 6 phosphatase; Islet specific glucose 6 phosphatase catalytic subunit related protein; G6PC2_HUMAN.
Gene ID
57818
Swiss Prot
Q9NQR9
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
191-290/355
Target
Glucose 6 phosphatase 2
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
57818
Predicted Cross Reactivity
Human, Dog, Cow, Horse, Rabbit
Curated Selection
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