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IKK gamma Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity) . Essential for viral activation of IRF3.

Synonyms

IkB kinase associated protein 1; IkB kinase subunit gamma; Inhibitor of nuclear factor kappa B kinase subunit gamma; AMCBX1; FIP 3; FIP3; Fip3p; I kappa B kinase gamma; IkB kinase associated protein 1; IkB kinase gamma subunit; IkB kinase subunit gamma; IKBKG; IKKAP 1; IKKAP1; IKKG; Incontinentia pigmenti; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase gamma; Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma; Inhibitor of nuclear factor kappa B kinase gamma subunit; Inhibitor of nuclear factor kappa B kinase subunit gamma; IP 1; IP 2; IP; IP1; IP2; IPD2; NEMO; NF kappa B essential modifier; NF kappa B essential modulator; NF kappaB essential modifier; NF kappaB essential modulator; NFkappaB essential modulator.

Gene ID

8517

Swiss Prot

Q9Y6K9

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

301-400/419

Target

IKK gamma

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human IKK gamma

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8517

Predicted Cross Reactivity

Mouse, Rat, Cow, Sheep, Pig

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