ZNT8 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].
Synonyms
SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; Zinc transporter 8; zinc transporter ZnT-8; ZnT-8; ZNT 8; ZNT8_HUMAN.
Gene ID
169026
Swiss Prot
Q8IWU4
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Immunogen
1-100/369
Target
ZNT8
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human ZNT8
Applications
IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
169026
Predicted Cross Reactivity
Human, Mouse
Curated Selection
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