ZNT8 Polyclonal Antibody, Biotin Conjugated

ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].

SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; Zinc transporter 8; zinc transporter ZnT-8; ZnT-8; ZNT 8; ZNT8_HUMAN.