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ZNT8 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].

Synonyms

SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; Zinc transporter 8; zinc transporter ZnT-8; ZnT-8; ZNT 8; ZNT8_HUMAN.

Gene ID

169026

Swiss Prot

Q8IWU4

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

1-100/369

Target

ZNT8

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from human ZNT8

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1µg/µl

Dilution

IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

169026

Predicted Cross Reactivity

Human, Mouse

Curated Selection

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