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BTR1 Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration (By similarity) . Involved in borate homeostasis. In the absence of borate, it functions as a Na (+) and OH (-) (H (+) ) channel. In the presence of borate functions as an electrogenic Na (+) coupled borate cotransporter.

Synonyms

BT R1; NaBC1; SLC4A11; sodium bicarbonate transporter-like protein 11; solute carrier family 4 member 11; S4A11_HUMAN.

Gene ID

83959

Swiss Prot

Q8NBS3

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

61-160/891

Target

BTR1

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human BTR1

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

83959

Predicted Cross Reactivity

Mouse, Rat

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