GASC1/KDM4C Polyclonal Antibody, PerCP Conjugated

Product Specifications

Background

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Synonyms

GASC 1 protein; GASC1 antibody Gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain containing histone demethylation protein 3C; Jumonji domain containing protein 2C; KDM4C_HUMAN.

Gene ID

23081

Swiss Prot

Q9H3R0

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

291-390/1056

Target

GASC1/KDM4C

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human GASC1/KDM4C

Applications

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

23081

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit

Curated Selection

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