HOXD10 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Synonyms
Homeo box D10; Homeobox protein Hox-4D; Homeobox protein Hox-4E; Homeobox protein Hox-D10; Hox 4.5; Hox 4D; Hox 4E; HOX4D; HOXD10; HXD10; HXD10_HUMAN; Hox 5.3.
Gene ID
3236
Swiss Prot
P28358
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
111-210/340
Target
HOXD10
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human HOXD10
Applications
IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3236
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
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