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HOXD10 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]

Synonyms

Homeo box D10; Homeobox protein Hox-4D; Homeobox protein Hox-4E; Homeobox protein Hox-D10; Hox 4.5; Hox 4D; Hox 4E; HOX4D; HOXD10; HXD10; HXD10_HUMAN; Hox 5.3.

Gene ID

3236

Swiss Prot

P28358

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

111-210/340

Target

HOXD10

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human HOXD10

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3236

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

Curated Selection

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