TLR7 agonist 6
TLR7 agonist 6 (compound IIb-19) is an TLR7 agonist with an EC50 value of 1.0 nM[1].
Product Specifications
CAS Number
[2380231-86-5]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr7-agonist-6.html
Purity
98.08
Solubility
10 mM in DMSO
Smiles
OC1=NC2=C(N1CC3=CC(OCCCCO4)=C(C5=CC=C(CNC6CCC6)C=C5)C=C3)N=C4N=C2N
Molecular Formula
C27H30N6O3
Molecular Weight
486.57
References & Citations
[1]Purandare AV, et al. Preparation of macrocyclic purine compounds as toll-like receptor 7 (TLR7) agonists: World Intellectual Property Organization, WO2019209811 A1. 2019-10-31.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7
Available Sizes
Curated Selection
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