KLF10 Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
KLF10 is a transcription factor that plays a role in the regulation of cell growth. It binds to the consensus sequence 5'-GGTGTG-3'. KLF10 plays a role in the response to TGFbeta (through the TGFbeta/Smad signalling pathway) and estrogen. In both cases, KLF10 induces or repressed gene transcription to enhance the TGFbeta/Smad signalling pathway, as well as other pathways, to regulate cell proliferation, differentiation and apoptosis. KLF10 has been shown to have a role in skeletal disease (osteopenia/osteoporosis), hypertrophic cardiomyopathy, and breast and prostate cancer.
Synonyms
TIEG1; TGF-beta inducible early growth response gene 1; Transforming growth factor-beta-inducible early growth response protein 1; Krueppel-like factor 10; TIEG-1; EGR-alpha; KLF10; TIEG; GDNF-inducible factor; Transcription factor GIF; mGIF; KLF10_HUMAN.
Gene ID
Q13118
Swiss Prot
7071
Host
Rabbit
Cross Reactivity
Mouse
Target
KLF10
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human KLF10
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
Q13118
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit
Curated Selection
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