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TEM1 Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.

Synonyms

TEM1; CD164L1; Endosialin; Tumor endothelial marker 1; CD248

Gene ID

57124

Swiss Prot

Q9HCU0

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

251-350/757

Target

TEM1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic peptide derived from human TEM 1

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

57124

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig, Horse

Available Sizes

Curated Selection

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