Didanosine

Didanosine (2',3'-Dideoxyinosine; ddI) is a a potent and orally active dideoxynucleoside analogue, and also is a potent nucleoside reverse transcriptase inhibitor. Didanosine shows antiretroviral activity for HIV[1][2][3].

Product Specifications

CAS Number

[69655-05-6]

Product Name Alternative

2',3'-Dideoxyinosine; ddI

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HIV; Reverse Transcriptase

Type

Oligonucleotides

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Didanosine.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC[C@@H]1CC[C@H](N2C3=C(N=C2)C(O)=NC=N3)O1

Molecular Formula

C10H12N4O3

Molecular Weight

236.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Munir N.Nassar, et al. Analytical profiles of drug substances and excipients. Journals & Books, 1993, 185-227.|[2]Caroline M. Perry, et al. Didanosine. Drugs, 1999, 58, 1099-1135.|[3]Braga Neto MB, et al. Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice. BMC Gastroenterol. 2010 Aug 11;10:90.