CCR4 Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G (i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Synonyms
CC chemokine receptor 4; chemokine (C-C motif) receptor 4; CC-CKR-4; CCR-4; CD194; CHEMOKINE CC4 RECEPTOR; CHEMR1; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5; LESTR; MGC151418; MGC88293; nocturnin, Sdf1r; chemokine C C motif receptor 4; ChemR13; CCR4_HUMAN; C-C chemokine receptor type 4; K5-5; CD 194; CD-194.
Gene ID
1233
Swiss Prot
P51679
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
171-220/360
Target
CCR4
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human CCR4
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1233
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