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Nkx2.5 Polyclonal Antibody

Product Specifications

Background

Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.

Synonyms

Csx; Nkx2.5; tinman; Nkx-2.5; Homeobox protein Nkx-2.5; Cardiac-specific homeobox; Homeobox protein CSX; Homeobox protein NK-2 homolog E; Nkx2-5; Nkx2e

Gene ID

18091

Swiss Prot

P42582

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

85-180/324

Target

Nkx2.5/Cardiac-specific homeobox 1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from mouse Nkx2.5

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

18091

Predicted Cross Reactivity

Mouse, Dog, Cow, Pig, Rabbit

Available Sizes

Curated Selection

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