Bcl-2 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Synonyms
Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B cell lymphoma 2; Bcl 2; Bcl-2; Bcl2; BCL2 protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma, B-cell, 2; Oncogene B-cell leukemia 2; BCL2_HUMAN.
Gene ID
596
Swiss Prot
P10415
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
151-239/239
Target
Bcl-2
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human Bcl-2
Applications
WB, FCM
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
596
Predicted Cross Reactivity
Mouse, Cow, Sheep, Pig
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6386943-01 0.1 mL
NFATC4 (Nuclear Factor of Activated T-cells, Cytoplasmic 4, NF-ATc4, NFATc4, T-cell Transcription Factor NFAT3, NF-AT3, NFAT3) (Biotin)
Ask
View Details MBS6386943-02 5x 0.1 mL
NFATC4 (Nuclear Factor of Activated T-cells, Cytoplasmic 4, NF-ATc4, NFATc4, T-cell Transcription Factor NFAT3, NF-AT3, NFAT3) (Biotin)
Ask
View Details 
MBS6244287-01 0.1 mL
CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1, INCAM-110) (PE)
Ask
View Details MBS6244287-02 5x 0.1 mL
CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1, INCAM-110) (PE)
Ask
View Details