Phospho-delta Opioid Receptor (Ser363) Polyclonal Antibody, PE-Cy5.5 Conjugated
Product Specifications
Background
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Synonyms
OPRD; Delta-type opioid receptor; D-OR-1; DOR-1; OPRD1
Gene ID
4985
Swiss Prot
P41143
Modification Site
Ser363
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-delta Opioid Receptor (Ser363)
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5.5
Source
KLH conjugated synthetic peptide derived from human OPRD1 around the phosphorylation site of TP (p-S) DG
Applications
WB, FCM
Purification
Purified by Protein A.
Excitation Emission
488nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This phosphorylation site is homologous in the listed cross reactive species at the specified location.
Gene ID URL
4985
Predicted Cross Reactivity
Cow, Chicken, Rabbit
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