Phospho-delta Opioid Receptor (Ser363) Polyclonal Antibody, PE Conjugated

Product Specifications

Background

G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Synonyms

OPRD; Delta-type opioid receptor; D-OR-1; DOR-1; OPRD1

Gene ID

4985

Swiss Prot

P41143

Modification Site

Ser363

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-delta Opioid Receptor (Ser363)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human OPRD1 around the phosphorylation site of TP (p-S) DG

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous in the listed cross reactive species at the specified location.

Gene ID URL

4985

Predicted Cross Reactivity

Cow, Chicken, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ABC-KD6810 1 Vial

Human HIST1H4C knockdown cell line

Ask

View Details

ELI-44255b 96 Tests

Bovine Protein yippee-like 5, YPEL5 ELISA KIT

Ask

View Details

E47M51043 100 µL

PDK2 Mouse mAb

Ask

View Details

250599-ML550 100 µL

PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, non-ATPase, 7, MOV34, P40, Rpn8, S12) (MaxLight 550)

Ask

View Details

TA814363 100 µL

NGAL (LCN2) Mouse Monoclonal Antibody [Clone ID: OTI3F5]

Ask

View Details

GTR15375068 1 Vial

Lentiviral human CYP2C19 sgRNA gene knockout kit - Lentiviral human CYP2C19 sgRNA gene knockout kit (plasmid)

Ask

View Details