Phospho-delta Opioid Receptor (Ser363) Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Synonyms

OPRD; Delta-type opioid receptor; D-OR-1; DOR-1; OPRD1

Gene ID

4985

Swiss Prot

P41143

Modification Site

Ser363

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-delta Opioid Receptor (Ser363)

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human OPRD1 around the phosphorylation site of TP (p-S) DG

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous in the listed cross reactive species at the specified location.

Gene ID URL

4985

Predicted Cross Reactivity

Cow, Chicken, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E55B0732 100 µg

Cemiplimab (Reference antibody)

Ask

View Details

EK241525 96 Well

Rat TGFb2 (Transforming Growth Factor Beta 2) ELISA Kit

Ask

View Details

abx918358-01 15 nmol

Mouse GPC5 siRNA

Ask

View Details

abx918358-02 30 nmol

Mouse GPC5 siRNA

Ask

View Details

TL314796V 500 µL Each

ANGPTL2 Human shRNA Lentiviral Particle (Locus ID 23452)

Ask

View Details

ABC-KH10982 1 Vial

Human OTP knockout cell line

Ask

View Details