Phospho-delta Opioid Receptor (Ser363) Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Synonyms
OPRD; Delta-type opioid receptor; D-OR-1; DOR-1; OPRD1
Gene ID
4985
Swiss Prot
P41143
Modification Site
Ser363
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-delta Opioid Receptor (Ser363)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human OPRD1 around the phosphorylation site of TP (p-S) DG
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Specificity
This phosphorylation site is homologous in the listed cross reactive species at the specified location.
Gene ID URL
4985
Predicted Cross Reactivity
Cow, Chicken, Rabbit
Curated Selection
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