CBY1 Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Synonyms
CBY; arb1; PGEA1; C22orf2; PIGEA14; PIGEA-14; HS508I15A; Protein chibby homolog 1; ARPP-binding protein; Cytosolic leucine-rich protein; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; CBY1; HRIHFB2025
Gene ID
25776
Swiss Prot
Q9Y3M2
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
51-126/126
Target
CBY1
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human CBY1
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
25776
Predicted Cross Reactivity
Human
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