S100B Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Synonyms
NEF; S1; S1-B; S1beta; Protein S1-B; S-1 protein beta chain; S-1 protein subunit beta; S1 calcium-binding protein B; S1B
Gene ID
6285
Swiss Prot
P04271
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
31-92/92
Target
S100B
Clonality
Polyclonal
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human S100B
Applications
ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6285
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC217577L3 10 µg
Rad51L1 (RAD51B) (NM_002877) Human Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
R1075-10L-HRP 100 µL
RANKL (Receptor Activator of Nuclear Factor kappa B Ligand, Receptor Activator of NFkB Ligand, CD254, hRANKL2, hRANKL-2, Osteoclast Differentiation Factor, ODF, Osteoprotegerin Ligand, OPGL, sOdf, SOFA, TNF-related Activation-induced Cytokine, TRANCE, Tumor Necrosis Factor Ligand Superfamily Member 11, Tumor Necrosis Factor Superfamily Member 11, TNFSF11) (HRP) discontinued
Sign In for Pricing
View Details 038156-APC 200 µL
MAP4K2, ID (MAP4K2, GCK, RAB8IP, Mitogen-activated protein kinase kinase kinase kinase 2, B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, Rab8-interacting protein) (APC) discontinued
Sign In for Pricing
View Details 
YWC73365-01 50 mg
N, N-Dimethyl-2,3-dihydro-1H-isoindole-5-sulfonamide hydrochloride
Sign In for Pricing
View Details YWC73365-02 100 mg
N, N-Dimethyl-2,3-dihydro-1H-isoindole-5-sulfonamide hydrochloride
Sign In for Pricing
View Details