RanBP3 Polyclonal Antibody, PE-Cy5.5 Conjugated
Product Specifications
Background
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
Synonyms
Ran-binding protein 3; RanBP3
Gene ID
8498
Swiss Prot
Q9H6Z4
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
441-540/567
Target
RanBP3
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5.5
Source
KLH conjugated synthetic peptide derived from human RanBP3
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8498
Predicted Cross Reactivity
Human, Mouse, Dog, Pig, Chicken
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
126287-HRP 100 µL
ELK4 (ETS Domain-containing Protein Elk-4, Serum Response Factor Accessory Protein 1, SAP-1, SRF Accessory Protein 1, SAP1) (HRP)
Ask
View Details 041728-PE 200 µL
SIAH2, ID (SIAH2, E3 ubiquitin-protein ligase SIAH2, Seven in absentia homolog 2) (PE) discontinued
Ask
View Details 