RanBP3 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
Synonyms
Ran-binding protein 3; RanBP3
Gene ID
8498
Swiss Prot
Q9H6Z4
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
441-540/567
Target
RanBP3
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human RanBP3
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8498
Predicted Cross Reactivity
Human, Mouse, Dog, Pig, Chicken
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880745-100 1x 100 µL
CD45 / LCA (2B11 + PD7/26), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040676-100 1x 100 µL
MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470700-500 1x 500 µL
MART-1 / Melan-A (M2-7C10 + M2-9E3 + A103), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040178-500 1x 500 µL
CD50 (ICAM-3) (186-2G9), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 