MITF Polyclonal Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR) . Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) . Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Synonyms
MI; WS2; CMM8; WS2A; bHLHe32; Microphthalmia-associated transcription factor; Class E basic helix-loop-helix protein 32; MITF
Gene ID
4286
Swiss Prot
O75030
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
351-450/526
Target
MITF
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human MITF
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4286
Predicted Cross Reactivity
Rat, Dog, Cow, Horse, Chicken, Rabbit
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
FT101P1000W Pack of 25
Pack of 25 Folded Technical Creped Filter 160G/M², 1000 Mm
Sign In for Pricing
View Details 
358253-01 48 Tests
PP (Pepsin) BioAssayTM ELISA Kit (Mouse) discontinued
Sign In for Pricing
View Details 358253-02 96 Tests
PP (Pepsin) BioAssayTM ELISA Kit (Mouse) discontinued
Sign In for Pricing
View Details