OMA1 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

Synonyms

Metalloendopeptidase OMA1, mitochondrial; OMA1; Metalloprotease-related protein 1; MPRP-1; Overlapping with the m-AAA protease 1 homolog; OMA1; MPRP1

Gene ID

115209

Swiss Prot

Q96E52

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

401-500/524

Target

OMA1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human OMA1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

115209

Predicted Cross Reactivity

Cow, Pig, Horse, Chicken, Cat, Rabbit, Zebrafish

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TP761282 50 µg

ZNF334 (NM_199441) Human Recombinant Protein

Ask

View Details

A16967-100 100 mg

Erythrosin B 100mg

Ask

View Details

SR300761 1 Kit

CEBPD Human siRNA Oligo Duplex (Locus ID 1052)

Ask

View Details

GTR15094653 1 Vial

Lentiviral human ZNF846 shRNA (UAS) - Lentiviral human ZNF846 shRNA (UAS, GFP) (100)

Ask

View Details

MBS7068315 Inquire

Recombinant Vibrio splendidus Protein CysZ homolog (cysZ), partial

Ask

View Details