Phospho-nNOS (Ser1417) Polyclonal Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Synonyms
MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
Gene ID
842
Swiss Prot
P55211
Modification Site
Ser1417
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat, Xenopus laevis
Target
Phospho-nNOS (Ser1417)
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated Synthesised phosphopeptide derived from human nNOS around the phosphorylation site of Ser1417
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
842
Predicted Cross Reactivity
Mouse, Zebrafish
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
S1014-18K1-APC 200 µL
SLC2A4 Regulator, CT (SLC2A4RG, GLUT4 Enhancer Factor, GEF, Huntington Disease Gene Regulatory Region Binding Protein 1, HDBP 1, HDBP1, HDBP-1) (APC) discontinued
Ask
View Details 
MBS6471561-01 0.2 mL
CYP2C18, CT (Cytochrome P450 2C18, CYPIIC18, Cytochrome P450-6B/29C) (FITC)
Ask
View Details MBS6471561-02 5x 0.2 mL
CYP2C18, CT (Cytochrome P450 2C18, CYPIIC18, Cytochrome P450-6B/29C) (FITC)
Ask
View Details