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NHP2 Polyclonal Antibody, Cy7 Conjugated

Product Specifications

Background

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

Synonyms

DKCB2; FLJ20479; H/ACA ribonucleoprotein complex subunit 2; NHP2; NHP2 like protein; NHP2 ribonucleoprotein; NHP2 ribonucleoprotein homolog (yeast) 1; NHP2 ribonucleoprotein homolog; NHP2, S. cerevisiae, homolog of; NHP2_HUMAN; NHP2P; NOLA2; Nucleolar protein family A member 2 (H/ACA small nucleolar RNPs) ; Nucleolar protein family A member 2; snoRNP protein NHP2.

Gene ID

55651

Swiss Prot

Q9NX24

Host

Rabbit

Cross Reactivity

Human

Immunogen

1-80/153

Target

NHP2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human NHP2

Applications

IF (ICC), IF

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1µg/µl

Dilution

IF (ICC) (1:50-200), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

55651

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Horse, Rabbit

Curated Selection

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