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Phospho-Nephrin (Tyr1217) Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity) .

Synonyms

CNF; NPHN; nephrin; Renal glomerulus-specific cell adhesion receptor; NPHS1

Gene ID

4868

Swiss Prot

O60500

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

Phospho-Nephrin (Tyr1217)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic phosphopeptide derived from human Nephrin around the phosphorylation site of Tyr1217.

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous to that of Tyr1232 in Mouse and Tyr1228 Rat.

Gene ID URL

4868

Predicted Cross Reactivity

Mouse, Rat

Curated Selection

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