Phospho-Nephrin (Tyr1217) Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
Product Specifications
Background
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity) .
Synonyms
CNF; NPHN; nephrin; Renal glomerulus-specific cell adhesion receptor; NPHS1
Gene ID
4868
Swiss Prot
O60500
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Nephrin (Tyr1217)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 750
Source
KLH conjugated synthetic phosphopeptide derived from human Nephrin around the phosphorylation site of Tyr1217.
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
749nm/775nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This phosphorylation site is homologous to that of Tyr1232 in Mouse and Tyr1228 Rat.
Gene ID URL
4868
Predicted Cross Reactivity
Mouse, Rat
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