Phospho-Nephrin (Tyr1217) Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity) .

Synonyms

CNF; NPHN; nephrin; Renal glomerulus-specific cell adhesion receptor; NPHS1

Gene ID

4868

Swiss Prot

O60500

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

Phospho-Nephrin (Tyr1217)

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic phosphopeptide derived from human Nephrin around the phosphorylation site of Tyr1217.

Applications

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous to that of Tyr1232 in Mouse and Tyr1228 Rat.

Gene ID URL

4868

Predicted Cross Reactivity

Mouse, Rat

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