Phospho-Nephrin (Tyr1217) Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity) .
Synonyms
CNF; NPHN; nephrin; Renal glomerulus-specific cell adhesion receptor; NPHS1
Gene ID
4868
Swiss Prot
O60500
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Nephrin (Tyr1217)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic phosphopeptide derived from human Nephrin around the phosphorylation site of Tyr1217.
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This phosphorylation site is homologous to that of Tyr1232 in Mouse and Tyr1228 Rat.
Gene ID URL
4868
Predicted Cross Reactivity
Mouse, Rat
Curated Selection
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