Phospho-Nephrin (Tyr1217) Polyclonal Antibody
Product Specifications
Background
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity) .
Synonyms
CNF; NPHN; nephrin; Renal glomerulus-specific cell adhesion receptor; NPHS1
Gene ID
4868
Swiss Prot
O60500
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Nephrin (Tyr1217)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic phosphopeptide derived from human Nephrin around the phosphorylation site of Tyr1217.
Applications
WB, ELISA, IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Specificity
This phosphorylation site is homologous to that of Tyr1232 in Mouse and Tyr1228 Rat.
Gene ID URL
4868
Predicted Cross Reactivity
Mouse, Rat
Curated Selection
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